In Vitro Bactericidal and Virucidal Efficacy of Povidone-Iodine Gargle/Mouthwash Against Respiratory and Oral Tract Pathogens
Identifieur interne : 000942 ( Main/Exploration ); précédent : 000941; suivant : 000943In Vitro Bactericidal and Virucidal Efficacy of Povidone-Iodine Gargle/Mouthwash Against Respiratory and Oral Tract Pathogens
Auteurs : Maren Eggers [Allemagne] ; Torsten Koburger-Janssen [Allemagne] ; Markus Eickmann [Allemagne] ; Juergen Zorn [Allemagne]Source :
- Infectious Diseases and Therapy [ 2193-8229 ] ; 2018.
Abstract
Recent virus epidemics and rising antibiotic resistance highlight the importance of hygiene measures to prevent and control outbreaks. We investigated the in vitro bactericidal and virucidal efficacy of povidone-iodine (PVP-I) 7% gargle/mouthwash at defined dilution against oral and respiratory tract pathogens.
PVP-I was tested against
PVP-I gargle/mouthwash diluted 1:30 (equivalent to a concentration of 0.23% PVP-I) showed effective bactericidal activity against
PVP-I 7% gargle/mouthwash showed rapid bactericidal activity and virucidal efficacy in vitro at a concentration of 0.23% PVP-I and may provide a protective oropharyngeal hygiene measure for individuals at high risk of exposure to oral and respiratory pathogens.
Mundipharma Research GmbH & Co. KG (MRG).
Url:
DOI: 10.1007/s40121-018-0200-7
PubMed: 29633177
PubMed Central: 5986684
Affiliations:
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sortKey="Koburger Janssen, Torsten" sort="Koburger Janssen, Torsten" uniqKey="Koburger Janssen T" first="Torsten" last="Koburger-Janssen">Torsten Koburger-Janssen</name><affiliation wicri:level="1"><nlm:aff id="Aff2">Hygiene Nord GmbH, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hygiene Nord GmbH, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Eickmann, Markus" sort="Eickmann, Markus" uniqKey="Eickmann M" first="Markus" last="Eickmann">Markus Eickmann</name><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1936 9756</institution-id><institution-id institution-id-type="GRID">grid.10253.35</institution-id><institution>Institute for Virology,</institution><institution>Philipps University of Marburg,</institution></institution-wrap>Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Marburg</wicri:regionArea></affiliation></author><author><name sortKey="Zorn, Juergen" sort="Zorn, Juergen" uniqKey="Zorn J" first="Juergen" last="Zorn">Juergen Zorn</name><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0390 9594</institution-id><institution-id institution-id-type="GRID">grid.476538.b</institution-id><institution>Mundipharma Research GmbH & Co.KG,</institution></institution-wrap>Limburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Limburg</wicri:regionArea></affiliation></author></analytic><series><title level="j">Infectious Diseases and Therapy</title><idno type="ISSN">2193-8229</idno><idno type="eISSN">2193-6382</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p id="Par1">Recent virus epidemics and rising antibiotic resistance highlight the importance of hygiene measures to prevent and control outbreaks. We investigated the in vitro bactericidal and virucidal efficacy of povidone-iodine (PVP-I) 7% gargle/mouthwash at defined dilution against oral and respiratory tract pathogens.</p></sec><sec><title>Methods</title><p id="Par2">PVP-I was tested against <italic>Klebsiella pneumoniae</italic> and <italic>Streptococcus pneumoniae</italic> according to bactericidal quantitative suspension test EN13727 and against severe acute respiratory syndrome and Middle East respiratory syndrome coronaviruses (SARS-CoV and MERS-CoV), rotavirus strain Wa and influenza virus A subtype H1N1 according to virucidal quantitative suspension test EN14476. PVP-I 7% gargle/mouthwash was diluted 1:30 with water to a concentration of 0.23% (the recommended concentration for “real-life” use in Japan) and tested at room temperature under clean conditions [0.3 g/l bovine serum albumin (BSA), viruses only] and dirty conditions (3.0 g/l BSA + 3.0 ml/l erythrocytes) as an interfering substance for defined contact times (minimum 15 s). Rotavirus was tested without protein load. A ≥ 5 log<sub>10</sub> (99.999%) decrease of bacteria and ≥ 4 log<sub>10</sub> (99.99%) reduction in viral titre represented effective bactericidal and virucidal activity, respectively, per European standards.</p></sec><sec><title>Results</title><p id="Par3">PVP-I gargle/mouthwash diluted 1:30 (equivalent to a concentration of 0.23% PVP-I) showed effective bactericidal activity against <italic>Klebsiella pneumoniae</italic> and <italic>Streptococcus pneumoniae</italic> and rapidly inactivated SARS-CoV, MERS-CoV, influenza virus A (H1N1) and rotavirus after 15 s of exposure.</p></sec><sec><title>Conclusion</title><p id="Par4">PVP-I 7% gargle/mouthwash showed rapid bactericidal activity and virucidal efficacy in vitro at a concentration of 0.23% PVP-I and may provide a protective oropharyngeal hygiene measure for individuals at high risk of exposure to oral and respiratory pathogens.</p></sec><sec><title>Funding</title><p id="Par5">Mundipharma Research GmbH & Co. KG (MRG).</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Berry, M" uniqKey="Berry M">M Berry</name></author><author><name sortKey="Gamieldien, J" uniqKey="Gamieldien J">J Gamieldien</name></author><author><name sortKey="Fielding, Bc" uniqKey="Fielding B">BC Fielding</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsieh, Yh" uniqKey="Hsieh Y">YH Hsieh</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Boyce, Jm" uniqKey="Boyce J">JM Boyce</name></author><author><name sortKey="Pittet, D" uniqKey="Pittet D">D Pittet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gralton, J" uniqKey="Gralton J">J Gralton</name></author><author><name sortKey="Tovey, Er" uniqKey="Tovey E">ER Tovey</name></author><author><name sortKey="Mclaws, Ml" uniqKey="Mclaws M">ML McLaws</name></author><author><name sortKey="Rawlinson, Wd" uniqKey="Rawlinson W">WD Rawlinson</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kitamura, T" uniqKey="Kitamura T">T Kitamura</name></author><author><name sortKey="Satomura, K" uniqKey="Satomura K">K Satomura</name></author><author><name sortKey="Kawamura, T" uniqKey="Kawamura T">T Kawamura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sneader, W" uniqKey="Sneader W">W Sneader</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mclure, Ar" uniqKey="Mclure A">AR McLure</name></author><author><name sortKey="Gordon, J" uniqKey="Gordon J">J Gordon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Traore, O" uniqKey="Traore O">O Traoré</name></author><author><name sortKey="Fayard, Sf" uniqKey="Fayard S">SF Fayard</name></author><author><name sortKey="Laveran, H" uniqKey="Laveran H">H Laveran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shimizu, M" uniqKey="Shimizu M">M Shimizu</name></author><author><name sortKey="Okuzumi, K" uniqKey="Okuzumi K">K Okuzumi</name></author><author><name sortKey="Yoneyama, A" uniqKey="Yoneyama A">A Yoneyama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gorman, Sp" uniqKey="Gorman S">SP Gorman</name></author><author><name sortKey="Scott, Em" uniqKey="Scott E">EM Scott</name></author><author><name sortKey="Hutchinson, Ep" uniqKey="Hutchinson E">EP Hutchinson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rikimaru, T" uniqKey="Rikimaru T">T Rikimaru</name></author><author><name sortKey="Kondo, M" uniqKey="Kondo M">M Kondo</name></author><author><name sortKey="Kondo, S" uniqKey="Kondo S">S Kondo</name></author><author><name sortKey="Oizumi, K" uniqKey="Oizumi K">K Oizumi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wutzler, P" uniqKey="Wutzler P">P Wutzler</name></author><author><name sortKey="Sauerbrei, A" uniqKey="Sauerbrei A">A Sauerbrei</name></author><author><name sortKey="Klocking, R" uniqKey="Klocking R">R Klöcking</name></author><author><name sortKey="Brogmann, B" uniqKey="Brogmann B">B Brögmann</name></author><author><name sortKey="Reimer, K" uniqKey="Reimer K">K Reimer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kawana, R" uniqKey="Kawana R">R Kawana</name></author><author><name sortKey="Kitamura, T" uniqKey="Kitamura T">T Kitamura</name></author><author><name sortKey="Nakagomi, O" uniqKey="Nakagomi O">O Nakagomi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kariwa, H" uniqKey="Kariwa H">H Kariwa</name></author><author><name sortKey="Fujii, N" uniqKey="Fujii N">N Fujii</name></author><author><name sortKey="Takashima, I" uniqKey="Takashima I">I Takashima</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eggers, M" uniqKey="Eggers M">M Eggers</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name></author><author><name sortKey="Kowalski, K" uniqKey="Kowalski K">K Kowalski</name></author><author><name sortKey="Zorn, J" uniqKey="Zorn J">J Zorn</name></author><author><name sortKey="Reimer, K" uniqKey="Reimer K">K Reimer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eggers, M" uniqKey="Eggers M">M Eggers</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name></author><author><name sortKey="Zorn, J" uniqKey="Zorn J">J Zorn</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Spearman, C" uniqKey="Spearman C">C Spearman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="K Rber, G" uniqKey="K Rber G">G Kärber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yoneyama, A" uniqKey="Yoneyama A">A Yoneyama</name></author><author><name sortKey="Shimizu, M" uniqKey="Shimizu M">M Shimizu</name></author><author><name sortKey="Tabata, M" uniqKey="Tabata M">M Tabata</name></author><author><name sortKey="Yashiro, J" uniqKey="Yashiro J">J Yashiro</name></author><author><name sortKey="Takata, T" uniqKey="Takata T">T Takata</name></author><author><name sortKey="Hikida, M" uniqKey="Hikida M">M Hikida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shiraishi, T" uniqKey="Shiraishi T">T Shiraishi</name></author><author><name sortKey="Nakagawa, Y" uniqKey="Nakagawa Y">Y Nakagawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ito, H" uniqKey="Ito H">H Ito</name></author><author><name sortKey="Ito, T" uniqKey="Ito T">T Ito</name></author><author><name sortKey="Hikida, M" uniqKey="Hikida M">M Hikida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sriwilaijaroen, N" uniqKey="Sriwilaijaroen N">N Sriwilaijaroen</name></author><author><name sortKey="Wilairat, P" uniqKey="Wilairat P">P Wilairat</name></author><author><name sortKey="Hiramatsu, H" uniqKey="Hiramatsu H">H Hiramatsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steinmann, J" uniqKey="Steinmann J">J Steinmann</name></author><author><name sortKey="Paulmann, D" uniqKey="Paulmann D">D Paulmann</name></author><author><name sortKey="Becker, B" uniqKey="Becker B">B Becker</name></author><author><name sortKey="Bischoff, B" uniqKey="Bischoff B">B Bischoff</name></author><author><name sortKey="Steinmann, E" uniqKey="Steinmann E">E Steinmann</name></author><author><name sortKey="Steinmann, J" uniqKey="Steinmann J">J Steinmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauerbrei, A" uniqKey="Sauerbrei A">A Sauerbrei</name></author><author><name sortKey="Wutzler, P" uniqKey="Wutzler P">P Wutzler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gottardi, W" uniqKey="Gottardi W">W Gottardi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanagalingam, J" uniqKey="Kanagalingam J">J Kanagalingam</name></author><author><name sortKey="Feliciano, R" uniqKey="Feliciano R">R Feliciano</name></author><author><name sortKey="Hah, Jh" uniqKey="Hah J">JH Hah</name></author><author><name sortKey="Labib, H" uniqKey="Labib H">H Labib</name></author><author><name sortKey="Le, Ta" uniqKey="Le T">TA Le</name></author><author><name sortKey="Lin, Jc" uniqKey="Lin J">JC Lin</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Nagatake, T" uniqKey="Nagatake T">T Nagatake</name></author><author><name sortKey="Ahmed, K" uniqKey="Ahmed K">K Ahmed</name></author><author><name sortKey="Oishi, K" uniqKey="Oishi K">K Oishi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Satomura, K" uniqKey="Satomura K">K Satomura</name></author><author><name sortKey="Kitamure, T" uniqKey="Kitamure T">T Kitamure</name></author><author><name sortKey="Kawamura, T" uniqKey="Kawamura T">T Kawamura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okuda, M" uniqKey="Okuda M">M Okuda</name></author><author><name sortKey="Kaneko, Y" uniqKey="Kaneko Y">Y Kaneko</name></author><author><name sortKey="Ichinohe, T" uniqKey="Ichinohe T">T Ichinohe</name></author><author><name sortKey="Ishihara, K" uniqKey="Ishihara K">K Ishihara</name></author><author><name sortKey="Okuda, K" uniqKey="Okuda K">K Okuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Madan, Pd" uniqKey="Madan P">PD Madan</name></author><author><name sortKey="Sequeira, Ps" uniqKey="Sequeira P">PS Sequeira</name></author><author><name sortKey="Shenoy, K" uniqKey="Shenoy K">K Shenoy</name></author><author><name sortKey="Shetty, J" uniqKey="Shetty J">J Shetty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rahn, R" uniqKey="Rahn R">R Rahn</name></author><author><name sortKey="Adamietz, Ia" uniqKey="Adamietz I">IA Adamietz</name></author><author><name sortKey="Boettcher, Hd" uniqKey="Boettcher H">HD Boettcher</name></author><author><name sortKey="Schaefer, V" uniqKey="Schaefer V">V Schaefer</name></author><author><name sortKey="Reimer, K" uniqKey="Reimer K">K Reimer</name></author><author><name sortKey="Fleischer, W" uniqKey="Fleischer W">W Fleischer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lanjri, S" uniqKey="Lanjri S">S Lanjri</name></author><author><name sortKey="Uwingabiye, J" uniqKey="Uwingabiye J">J Uwingabiye</name></author><author><name sortKey="Frikh, M" uniqKey="Frikh M">M Frikh</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Stuttgart</li></region><settlement><li>Stuttgart</li></settlement></list><tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Eggers, Maren" sort="Eggers, Maren" uniqKey="Eggers M" first="Maren" last="Eggers">Maren Eggers</name></region><name sortKey="Eickmann, Markus" sort="Eickmann, Markus" uniqKey="Eickmann M" first="Markus" last="Eickmann">Markus Eickmann</name><name sortKey="Koburger Janssen, Torsten" sort="Koburger Janssen, Torsten" uniqKey="Koburger Janssen T" first="Torsten" last="Koburger-Janssen">Torsten Koburger-Janssen</name><name sortKey="Zorn, Juergen" sort="Zorn, Juergen" uniqKey="Zorn J" first="Juergen" last="Zorn">Juergen Zorn</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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